Offenders forced entry to a business premises through a roller shutter door at Bewdley Business Park.
Once inside, they emptied a safe, and made off with metal products along with with motorcycle.
The incident happened overnight on Tuesday (oct3) and Wednesday (oct4).
Police said they believed the items were loaded onto a white van, with the limited edition Harley Davidson Orange V-Rod being ridden off in an unknown direction.
Two other premises on the business park were also broken into, but nothing was taken.
Anyone with details should call West Mercia Police on 101 or Crimestoppers anonymously on 0800 555 111.